SIGNAL (SIngle-cell Group techNical vAriations Learning)

SIGNAL is a R package for data integration by learning group technical variations.

Installation

To run SIGNAL, install from GitHub through devtools directly:

install.packages('devtools')
library(devtools)
devtools::install_github("yzhou1999/SIGNAL")

Usage

For usage examples, please see the vignettes directory of the repository.

• Supervised integration using SIGNAL
• Multi-scale analysis using SIGNAL
• Knowledge transfer from reference to query using SIGNAL

Dependencies

SIGNAL has been successfully installed and used on Windows, Linux and Mac OS (R version >= 4.0.2). The dependencies including: base, stats, Matrix, matrixStats, sparseMatrixStats, mclust, Rcpp, RcppEigen, irlba, BiocNeighbors, bigstatsr, dplyr, RSpectra.